This article is the second in a series of four articles that Computer is publishing to celebrate the 75th anniversary of the IEEE Computer Society (CS) this year. The first article published in the February 2021 issue gave an overview of socioeconomic transformations facilitated by computing technology during the past 75 years and looked at some of the key roles played by the CS to enable this change. In this article, we look at the major computing technologies enabling such transformations.