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The molting process in arthropods is regulated by steroid hormones acting via nuclear receptor proteins. The most common molting hormone is the ecdysteroid, 20-hydroxyecd[...]
2009 | Text | English | Faculty and Staff Works |
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2.
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Steroid signaling underlies developmental processes in animals. Mutations that impair steroidogenesis in the fruit fly Drosophila melanogaster provide tools to dissect st[...]
2004 | Text | English | Faculty and Staff Works |
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3.
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Mutants created by site-directed mutagenesis were used to elucidate the function of amino acids involved in ligand binding to ecdysteroid receptor (EcR) and heterodimer f[...]
2003 | Text | English | Faculty and Staff Works |
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Background: Genetic association studies demonstrate a relationship between several collagen gene variants and anterior cruciate ligament (ACL) injury, yet the mechanism o[...]
2012 | Text | English | Faculty and Staff Works |
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5.
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In both Manduca sexta and Drosophila melanogaster, metamorphic events are driven by ecdysteroids whose production in prothoracic gland (PGs) is stimulated periodically by[...]
1995 | Text | English | Faculty and Staff Works |
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Question: What do the Department of Homeland Security, Intel, and Disney have in common?1 Answer: The success of each depends on how efficiently they implement new techno[...]
2003 | Text | English | Faculty and Staff Works |
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Five water samples from three sources, two municipal reservoirs in central North Carolina and Toolik Lake in Alaska, were processed to conduct a comparative survey of mic[...]
2008 | Text | English | Faculty and Staff Works |
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8.
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The ultraspiracle (usp) gene encodes a nuclear receptor that forms a heterodimer with the ecdysone receptor (EcR) to mediate transcriptional responses to the insect stero[...]
2000 | Text | English | Faculty and Staff Works |
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9.
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The steroid hormone ecdysone initiates molting and metamorphosis in Drosophila via a heterodimeric receptor consisting of EcR that binds hormone, and USP, a homolog of th[...]
2001 | Text | English | Faculty and Staff Works |
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10.
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Ring glands dissected from homozygous l(3)ecd1ts wandering larvae and upshifted in vitro to the restrictive temperature, 29(degrees)C, synthesize abnormally low quantitie[...]
1987 | Text | English | Faculty and Staff Works |
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11.
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To assess the educational needs of North Carolina primary care physicians (PCPs) about direct-to-consumer (DTC) genetic testing, surveys were mailed to 2,402 family and i[...]
2012 | Text | English | Faculty and Staff Works |
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12.
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The usp locus encodes a member of the nuclear hormone receptor superfamily in Drosophila melaaogaater that interacts with EcR (ecdysone receptor) to mediate ecdysteroid-i[...]
1994 | Text | English | Faculty and Staff Works |
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13.
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Objective: Noise-induced hearing loss (NIHL) is a worldwide health problem and a growing concern among young people. Although some people appear to be more susceptible to[...]
2015 | Text | English | Faculty and Staff Works |
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Two forms, CtUSP-1 and CtUSP-2, of the Chironomus tentans homolog of Ultraspiracle (new nomenclature: Chironomus NR2B4) were described and verified as components of the f[...]
1999 | Text | English | Faculty and Staff Works |
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15.
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The functional insect ecdysteroid receptor is comprised of the ecdysone receptor (EcR) and Ultraspiracle (USP). The ligand-binding domain (LBD) of USP was fused to the GA[...]
2004 | Text | English | Faculty and Staff Works |
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16.
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In this paper, we examine the associations between specific candidate genes (DRD2, DRD4, COMT, biallelic and tri-allelic 5HTTLPR, and OXTR) and infant attachment outcomes[...]
2016 | Text | English | Faculty and Staff Works |
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17.
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This study assesses the importance of genetic differences that underlie differences in pupal diapause incidence among two lines of the flesh fly, Sarcophaga bullata. Line[...]
1983 | Text | English | Faculty and Staff Works |
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18.
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As an essential tool for risk stratification, family health history (FHH) is a central component of personalized medicine; yet, despite its widespread acceptance among pr[...]
2013 | Text | English | Faculty and Staff Works |
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19.
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The Genomic Medicine Model aims to facilitate patient engagement, patient/provider education of genomics/personalized medicine, and uptake of risk-stratified evidence-bas[...]
2014 | Text | English | Faculty and Staff Works |
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20.
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The fruit fly Drosophila melanogaster displays an ovarian diapause that is regulated by photoperiod. Newly eclosed female flies (Canton-S wild type) exposed to short days[...]
1989 | Text | English | Faculty and Staff Works |
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21.
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Physical activity is predictive of better cognitive performance and lower risk of Alzheimer's disease (AD). The apolipoprotein E gene (APOE) is a susceptibility gene for [...]
2015 | Text | Faculty and Staff Works |
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The in vitro production of juvenile hormone (JH) was investigated by using isolated ring glands from third instar Drosophila melanogaster. A JH-like molecule is secreted [...]
1989 | Text | English | Faculty and Staff Works |
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23.
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Insect development is guided by the combined actions of ecdysteroids and juvenile hormones (JHs). The transcriptional effects of ecdysteroids are mediated by a protein co[...]
2003 | Text | English | Faculty and Staff Works |
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24.
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The widely accepted paradigm that epoxidized methyl farnesoates ("juvenile hormones," JHs) are the principal sesquiterpenoid hormones regulating insect metamorphosis was [...]
2013 | Text | English | Faculty and Staff Works |
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25.
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Ecdysteroids (Ecs) enhance the formation of Ec receptor-ultraspiracle protein (EcR-USP) heterodimers which regulate gene transcription. To study EcR-USP heterodimerizatio[...]
2004 | Text | English | Faculty and Staff Works |
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