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facultystaff_1549_PDF
Genistein Induces Pancreatic (beta)Cell Proliferation through Activation of Multiple Signaling Pathways and Prevents Insulin-Deficient Diabetes i
Fu, Zhuo ; Zhang, Wen ; Zhen, Wei ; Lum, Hazel[...]
Genistein, a flavonoid in legumes and some herbal medicines, has various biological actions. However, studies on whether genistein has an effect on pancreatic (beta)cell [...]
2010 | Text | Faculty and Staff Works |
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facultystaff_1564_PDF
Phytoestrogen Genistein Protects Against Endothelial Barrier Dysfunction in Vascular Endothelial Cells Through PKA-Mediated Suppression of RhoA S
Jia, Zhenquan ; Zhen, Wei ; Babu, Pon Velayutham Anandh ; Liu, Dongmin
The soy-derived phytoestrogen genistein has received attention for its potential to improve vascular function, but its mechanism remains unclear. Here, we report that gen[...]
2013 | Text | English | Faculty and Staff Works |
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facultystaff_1566_PDF
Phytonutrient genistein is a survival factor for pancreatic (beta)cells via GPR30-mediated mechanism
Luo, Jing ; Wand, Aihua ; Zhen, Wei ; Wang, Yao[...]
We previously discovered that phytonutrient genistein rapidly activates cAMP signaling in (beta)cells and improves islet mass in diabetic mice. However, the mechanism und[...]
2018 | Text | Faculty and Staff Works |
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